Li Ruiqiang used to be head of bioinformatics center at BGI-Shenzhen and is currently the head of Scientific Research and Cooperation Division. He has been in charge of several large projects in the area of genomics and bioinformatics since 2007, such as Silkworm Project, Yanhuang Project, The Cucumber Initiative, The International Giant Panda Genome Project, The International 1000 Genomes Project and etc. He had also been involved in the rice genome project and chicken genome polymorphism project and etc. Research achievements were published on Science, PLos Biology, Nautre and etc. His research interests are mainly focused on genome assembly, gene and repeat annotation, gene express profiling, comparative genomics and molecular evolution.
Dr Severine Layec joined INRA to participate in the MetaHIT project, under the supervision of Pierre Renault, after completing a PhD on cell-wall synthesis in gram positive bacteria at Nancy University (France). Within WPF2, the question she will address is "What are the genes which may be involved in commensal life of Streptococcus salivarius"? To address this question, a mutagenesis will be performed on gene whose homologue have been filtered by statistical analysis of gene content in metagenomes performed by MetaHit partners. Mutant affected in these genes will be tested on an animal model in order to decipher their functions in microbiota and in relation with host health.
Dr. Denis Le Paslier (CEA/Genoscope) directs the "Metagenomics of Prokaryotes" research group and has been involved in the wastewater metagenomics project since its inception. He has authored more than 100 research papers.